Lynch syndrome is a genetic condition that increases the chances of developing cancer. In the case of colorectal cancer, it can multiply the risk by up to 40 times compared to a healthy individual..
Lynch syndrome is a hereditary condition that significantly increases a person's risk of developing colorectal cancer. It is caused by mutations in genes that are responsible for repairing damaged DNA. When these genes don't work properly, errors in DNA can accumulate, leading to the development of cancer. People with Lynch syndrome are more likely to develop colorectal cancer at a younger age and may develop multiple tumours.
If we look at colon cancer, it should be borne in mind that individuals with Lynch Syndrome present precursor lesions, adenomatous polyps, at an earlier age than the rest of the population. Furthermore, these polyps have a tendency to:
To be located in the right side of the colon
To be flat or depressed in shape, making it more difficult to identify
Presenting a much accelerated “progression” speed to cancer than in normal conditions (3-5 years in Lynch Syndrome vs. 15-20 years in the general population)
Screening tests, fundamental in colon cancer prevention
Given the foregoing, an adequate assessment of these patients in specialised consultations is essential, offering high-quality colonoscopy controls using chromoendoscopy advanced to identify and characterise such polyps.
Chromoendoscopy uses a contrast agent to stain the colon tissue. This way, It is more likely to detect flat polyps which tend to appear more frequently in people with Lynch syndrome.
The intervals between colonoscopies should be much shorter so that in the general population for adequate monitoring and to prevent progression to cancer.
If you suffer from or believe your family may suffer from Lynch Syndrome, please consult us.
Knowing that you or members of your family are at a higher risk of cancer is a difficult situation to face, but with appropriate advice, that knowledge can become the tool to protect the health of our loved ones.
At our centre Eating out in Madrid we offer you Specialised advice in relation to Lynch Syndrome and other hereditary syndromes, as well as the possibility of carrying out preventive procedures from chromoendoscopy or diagnostic genetic studies. We are here to help you!
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